KUNAMIN®  Grape Seed and Grape Skin Extract

KUNAMIN® is a new supplement containing grape product, which includes all the components of the grape. In experimental studies, it has been shown that proanthocyanidins contained in grape seeds inhibited some cell lines of cancer like human leukemia, melanoma, lung carcinoma and colon carcinoma, although no human experiments exist yet.1 On the other hand, polyphenols found in the skin of grapes worked in other cell lines or models, like lung carcinoma (mice), human epidermoid carcinoma, apoptosis in human lymphoma and gastric cancer.1 Chen demonstrated that grape seed extract attenuates Hepatitis C virus replication and virus-induced inflammation,2 and Park showed that resveratrol administration may help manage HBV-induced hepatocellular carcinoma.3 In an experimental model, Lin showed that resveratrol helped the liver to recover from fatty liver and also protected against the development of hepatocellular carcinoma induced by HBV.4 In an experimental study in mice, KUNAMIN® administration was associated with inhibition of HBV DNA replication while the product was administered.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure or prevent any disease.

Proprietary Blend
Grape Product         

  1. Santos-Buelga C, Scalbert A. Proanthocyanidins and tannin-like compounds – nature, occurrence, dietary intake and effects on nutrition and health. J Sci Food Agric. 2000;80(7):1094-1117
  2. Chen WC, Tseng CK, Cheng BH, Lin CK, Lee JC. Grape seed extract attenuates Hepatitis C virus replication and virus-induced inflammation. Front Pharmacol. 2016;7:490
  3. Park S, Lim J, Kim JR, Cho S. Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma. J Vet Sci. 2017;18(4):419-29
  4. Lin HC, Chen YF, Hsu WH, Yang CW, Kao CH, Tsai TF. Resveratrol Helps Recovery from Fatty Liver and Protects against Hepatocellular Carcinoma Induced by Hepatitis B Virus X Protein in a Mouse Model. Cancer Prev Res (Phila). 2012;5(7):952-62
  5. RAAS data on file


Related Items